Phytocheical Investigation On The Fruits Of Solanum Xanthocarpum

Abstract

The plant used for this study was Solanum xanthocarpum, a prickly diffuse, bright green perennial herb, locally known as enbuay. The aqueous extract of the fruit of the plant S. xanthocarpum is administered by some traditional healers for the treatment of tuberculosis, locally known as samba nekersa and other diseases. The phytochemical tests of S. zanthocarpum fruits revealed the presence of secondary metabolites such as alkaloids, flavonoids, phenolics, tannins and saponins in chloroform, ethyl acetate and methanol extracts. Then isolation and purification of phytoconstituents from chloroform and methanol extracts by column chromatography led to the isolation of two new compounds, one from each extract. Chloroform extract gave a simple 1, 2 di-substituted phenyl ester, which has not been reported before from this plant. And methanol extract gave a steroidal glycoside of furostane parent aglycone skeleton. The structures of both compounds have been elucidated by interpretation of their UV-Vs, IR, and NMR spectral data and comparison of these spectral data with literatures.