Bacterial Characterization, Antimicrobial Sensitivity Pattern And Associated Risk Factors Of Bacteriuria Among Pregnant Women Attending Selected Health Centers In Adama City, Ethiopia

Abstract

Urinary Tract Infection (Uti) Is Caused By The Presence And Growth Of Microorganisms Any Where In The Urinary Tract. Pregnant Women Are Quite Vulnerable To Uti-Causing Bacterial Pathogens Which Can Be Associated With Adverse Outcomes For Both The Mother And Fetus. This Study Aimed To Isolate And Characterize Bacterial Pathogens Causing Urinary Tract Infections In Pregnant Women, To Determine Antimicrobial Sensitivity Patterns, And To Assess Risk Factors Associated Withthe Infections At Adama City, Ethiopia. A Health Institution-Based Cross-Sectional Study Designwas Conducted And Midstream Urine Sample Was Collected From180 Pregnant Women Suspected Ofuti Attending Antenatal Clinics At Adama Health Center, Biftu Health Center, And Hangatu Health Center In Adama City From March 2024 To May 2024. Using A Structured Questionnaire,All Pregnant Women Were Interviewed Face To Face To Obtain The Social Demographic Profiles. Thewell-Mixed And Non-Centrifuged Urine Samples Were Inoculated Into 5% Sheep Blood Agar And Macconkey Agar Plates. It Was Incubated At 37??C For 24 Hours And Bacterial Colonies Were Characterized By Gram Stain And Biochemical Properties Of Isolates. The Prevalence Of Utiamong Pregnant Women In This Study Was 15.6%. E. Coli Was The Predominant Predictor Of Uti,Nine Pathogenic Bacteria Were Isolated, And 85.5% Of The Bacteria Were Gram-Negative. Pregnant Women Who Had A History Of Catheter Insertion And History Of Abortion Were Found Moresusceptible To Uti-Causing Bacteria. Most Of The Isolated Bacteria Were Susceptible To Ceftazidime And Meropenem. 85.7% Of The Bacterial Isolates Have Antibiotic Resistance For Atleast Two Antibiotics. 34.2% Of The Isolated Bacteria Showed Multi-Drug Resistance. The Study Areawill Need Further Analysis Of Utis Using Modern And Sensitive Diagnostic Methods Including Molecular Methods.